TY - JOUR AU - Kusuma, Ikhwan Yuda AU - Megasari, Peppy Octaviani Dian AU - Sukiatno, Linda PY - 2018/11/12 Y2 - 2024/03/28 TI - IDENTIFIKASI POTENSI INTERAKSI OBAT PADA PASIEN HIPERTENSI : STUDI RETROSPEKTIF RESEP POLIFARMASI DI APOTEK KARYA SEHAT PURWOKERTO JF - Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan JA - VM VL - 12 IS - 1 SE - Articles DO - 10.35960/vm.v11i2.426 UR - https://ejournal.uhb.ac.id/index.php/VM/article/view/426 SP - 72-80 AB - <p><em>ABSTRACT</em></p><p><em>&nbsp;</em></p><p><em>Hypertension is public health problem common in developing countries. </em><em>B</em><em>asic health research in 2013, the prevalence of hypertension in Indonesia is 26.5% with the largest proportion in Central Java </em><em>(</em><em>57.89%</em><em>)</em><em>. Outpatient</em><em> of</em><em> hypertension </em><em>is </em><em>tend to require two or more drugs (polypharmacy), </em><em>combination</em><em> antihypertension drugs or non antihypertension </em><em>drug</em><em>s when accompanied by coexisting illness. Polypharmacy can significantly increase the risk of drug interactions and </em><em>it</em><em>s an important factor in drug related problems that may affect patient outcome therapy. This study aims to determine the potential drug interactions in a patient's prescription in </em><em>Karya Sehat</em> <em>Pharmacy </em><em>Purwokerto. The method of this study was retrospective observational (March-May 2018). Data were analyzed descriptively using Stockley's Drug Interaction, Drug Interaction Facts, www.drugs.com database and Medscape Drug Interactions Checker. The results obtained by looking at the name of the drug listed in the prescription without considering the rules of use, drug dosage and the patient </em><em>condition was </em><em>showed potential drug interactions in </em><em>Karya Sehat</em> <em>Pharmacy </em><em>Purwokerto was 68.35% (n = 158 samples). The most mechanism pattern is pharmaco</em><em>dinami</em><em>c interaction (58,89%) and the most severity is moderate (65,74%).</em></p><p><em>&nbsp;</em></p><p><em>Keywords: hypertension, polypharmacy, pharmacy, potential drug interactions</em></p> ER -