Analysis of Antibiotic Drug Utilization in Pediatric Pneumonia Patients at Cilacap Regional Public Hospital Using the ATCDDD Method and DU 90%
DOI:
https://doi.org/10.35960/vm.v17i1.1437Keywords:
Antibiotic, Drug Utilization , Pediatric , Pneumonia , ATC/DDD , DU 90%Abstract
The high incidence of infectious pneumonia will increase the use of antibiotics. This disease is a leading cause of death in children under 5 years of age. This study aims to describe the utilization of antibiotics for pneumonia in pediatric patients aged ≤ 5 who were treated at RSUD Cilacap in 2022. The research method used was a descriptive study with retrospective data collection, referring to medical record data. Samples were taken using the total sampling method and evaluated using the ATC/DDD and DU 90% methods. The results showed that male pediatric patients were more prevalent (55.55%) with the highest age group being 0-1 years (40.27%). The most frequently used antibiotic was Ceftriaxone (45.06%). The highest DDD/100 bed days value was for Azithromycin at 52.14, and the lowest DDD/100 bed days value was for Metronidazole at 0.31. The antibiotic with the highest DU 90% value was Azithromycin (65.18). The results of the study can be concluded that elevated overall DDD/100 days value suggests that the greater the utilization of antibiotics within a 100-day treatment period, while the extensive inclusion of drugs in 90% DU segment indicates a less discerning approach to antibiotic selection in therapy
References
Abuka, T. (2017). Prevalence of pneumonia and factors associated among children 2-59 months old in Wondo Genet district, Sidama zone, SNNPR, Ethiopia. Current Pediatric Research, 21(1), 19–25.
Amare1, R. A., Fisseha2, G., Berhe2, A., & Tirore3, L. L. (2021). Incidence of recovery from severe pneumonia and its predictors among children 2–59 months admitted to pediatric ward of Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia: A retrospective Cohort study. Journal of Family Medicine and Primary Care, 6(2), 169–170. https://doi.org/10.4103/jfmpc.jfmpc
Andriani, Y., Martua, A. S., & Andriani, M. (2021). Evaluasi Penggunaan Antibiotik Dengan Metode Atc/Ddd Dan Du 90% Di Puskesmas Aur Duri Kota Jambi Periode 2016-2018. Jurnal Ilmiah As-Syifaa, 12(2), 91–98. https://doi.org/10.33096/jifa.v12i2.628
Aseng, C. R., Wiyono, W. I., & Jayanti, M. (2023). Evaluasi Penggunaan Antibiotik pada Pasien Covid-19 di RSUP Prof. Dr.R. D. Kandou Manado Periode Januari-Maret 2021. Pharmacon12(1), 77–82.
Azyenela, L., Tobat, S. R., & Selvia, L. (2022). Evaluasi Penggunaan Antibiotik di Instalasi Rawat Inap Bedah RSUD M. Natsir Kota Solok Tahun 2020. Jurnal Mandala Pharmacon Indonesia, 8(1), 1-10.
Dinkes Cilacap. (2021). Buku Profil Kesehatan Kabupaten Cilacap Tahun 2021.
Hanifah, S., Melyani, I., Madalena, L. (2022). Evaluasi Penggunaan Antibiotik Dengan Metode ATC/DDD dan DU 90% Pada Pasien Rawat Inap Kelompok Staff Medik Penyakit Dalam Di Salah Satu Rumah Sakit Swasta Di Kota Bandung. Farmaka VO.20(1)
Juwita, D., & Maharani, A. (2023). Profile of Antibiotic Use in Pediatric Patients with Pneumonia at Dr. M. Djamil Hospital Padang, West Sumatra, Indonesia. International Journal of Innovative Science and Research Technology.https://doi.org/10.5281/zenodo.7889096
Kemenkes RI. (2021) Profil Kesehatan Indonesia. In Pusdatin.Kemenkes.Go.Id. https://www.kemkes.go.id/downloads/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-2021.pdf
Kiconco, G., Turyasiima, M., Ndamira, A., Yamile, O. A., Egesa, W. I., Ndiwimana, M., & Maren, M. B. (2021). Prevalence and associated factors of pneumonia among under-fives with acute respiratory symptoms: a cross sectional study at a Teaching Hospital in Bushenyi District, Western Uganda. African Health Sciences, 21(4), 1701–1710. https://doi.org/10.4314/ahs.v21i4.25
Kuti, B. P., Adegoke, S. A., Oyelami, O. A., & Ota, M. O. (2014). Predictors of prolonged hospitalisation in childhood pneumonia in a rural health centre. SAJCH South African Journal of Child Health, 8(1), 11–15. https://doi.org/10.7196/SAJCH.663
Mackenzie, G. (2016). The definition and classification of pneumonia. Pneumonia. DOI 10.1186/s41479-016-0012-z
Mahmudah, F., Sumiwi, S. A., & Hartini, S. (2016). Study of the Use of Antibiotics with ATC/DDD System and DU 90% in Digestive Surgery in Hospital in Bandung. Indonesian Journal of Clinical Pharmacy, 5(4), 293–298. https://doi.org/10.15416/ijcp.2016.5.4.293
Nalang, A., Citraningtyas, G., & Lolo, W. A. (2018). Analisis Efektivitas Biaya (Cost Effectiveness Analysis) Pengobatan Pneumonia Menggunakan Antibiotik. Jurnal Ilmiah Farmasi, 7(3), 321–329.
Pani, S., Barliana, M. I., Halimah, E., Pradipta, I. S., & Annisa, N. (2015). Monitoring the Use of Antibiotics by the ATC/DDD Method and DU 90%: Observational Studies in Community Health Service Centers in North Gorontalo District. Indonesian Journal of Clinical Pharmacy, 4(4), 275–280. https://doi.org/10.15416/ijcp.2015.4.4.280
Parisa, N., Parulian, T., & Adelia, R. A. A. (2022). Rasionalitas Penggunaan Azitromisin pada Pasien ISPA di Rumah Sakit Moh. Hoesin (RSMH) Palembang. Jurnal Mandala Pharmacon Indonesia, 8(1), 34–48. https://doi.org/10.35311/jmpi.v8i1.160
Prasetya, A. A. N. P. R., Wijaya, I. G. E. J. S., & Kurnianta, P. D. M. (2023). Evaluasi Penggunaan Antibiotik dengan Metode ATC/DDD dan DU90% pada Pasien Pneumonia di RSD X Tahun 2022. Jurnal Mandala Pharmacon Indonesia, 9(2), 408–418. https://doi.org/10.35311/jmpi.v9i2.398
Rahmah, F. H. (2022). Evaluasi Penggunaan Antibiotik Pada Pasien Pneumonia Di Instalasi Rawat Inap RS Wava Husada Kepanjen Dengan Metode ATC/DDD. Skripsi,
Rashid, M. M., Chisti, M. J., Akter, D., Sarkar, M., & Chowdhury, F. (2017). Antibiotic use for pneumonia among children under-five at a pediatric hospital in Dhaka city, Bangladesh. Patient Preference and Adherence, 11, 1335–1342. https://doi.org/10.2147/PPA.S140002
Ridwan, A., Narulita, L., Widyadi, E. D., & Suharjono, S. (2019). Analisis Penggunaan Antibiotika pada Pasien Penyakit Dalam di RSUD Dr. H. Slamet Martodirdjo Pamekasan dengan Metode ATC/DDD. Jurnal Sains Farmasi & Klinis, 6(3), 237. https://doi.org/10.25077/jsfk.6.3.237-242.2019
Roselany, R., & Surjono, E. (2023). Pneumonia Clinical Features in Under-Five Children Treated in Atma Jaya Hospital in 2017-2020. Majalah Kedokteran Bandung, 55(1), 21–26. https://doi.org/10.15395/mkb.v55n1.2966
Supriani, B., & Wulandari, Y. F. (2022). Factors related to the incidence of pneumonia in toddlers at the Padang Guci Community Health Center , Kaur District , in 2022. 1(1), 13–18.
Surya, N. K. (2014). Analisis Implemasi Kebijakan Penggunaan Antibiotika Rasional Untuk Mencegah Resistensi Antibiotika di RSUP Sanglah Denpasar : Studi Infeksi. Jurnal Administrasi Kebijakan Kesehatan, 1(1), 43–50.
Teguh Hary Kartono, D. A. (2023). Analisis Efektivitas Biaya Penggunaan Antibiotik Pada Pasien Pneumonia Di Instalasi Rawat Inap RSU Muhammadiyah Siti Aminah Bumiayu Pada Tahun 2021. Pharmacy Peradaban Journal. Vol 3(1), 83–92.
WHO. (2022). WHO Guidelines for ATC Classification and DDD Assignment 25th Edition. Norwegian Institute, Norway
Zahra, N. L., Yuniarti, E., Ainni, A. N., & Fitri, D. (2023). Evaluasi Penggunaan Antibiotik Pada Pasien Pneumonia Dengan Metode Atc/Ddd Dan Du 90% Di Rawat Inap Rumah Sakit Umum Purbowangi Periode Tahun 2020-2022. Usadha: Journal of Pharmacy, 2(4), 535–542. https://jsr.lib.ums.ac.id/index.php/ujp
Zanichelli, V., Sharland, M., Cappello, B., Moja, L., Getahun, H., Pessoa-silva, C., Sati, H., Weezenbeek, C. Van, Balkhy, H., & Simão, M. (2023). & Practice of Antimicrobial Resistance. December 2022, 290–296.
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