Standardisasi Parameter Spesifik dan Non Spesifik Ekstrak Etanol Buah Asam Gelugur (GarciniaAatroviridis Griff.)
DOI:
https://doi.org/10.35960/vm.v11i02.459Keywords:
Keywords: Acid gelugur, specific parameter, non-spesific parameterAbstract
Acid gelugur fruit (Garcinia atroviridis) is one of the Garcinia families that has long been used as traditional medicine. Gelugur acid has been widely used as a cooking spice by Malay people, but it also has the ability to reduce cholesterol. Besides that, it has antioxidant properties and can reduce body weight and cholesterol. The purpose of this study was to establish specific parameter standards and non-specific parameters from the ethanol extract of acid gelugur fruit. The extract was obtained by maceration method using 70% ethanol with a rendament of 37.15%. Specific parameters include observations of organoleptic extracts of tamarind fruit showed, dark brown, distinctive smelling, and sour. Contains several sekendur metabolites such as flavonoids and saponins. The level of the compound that is soluble in water is 3.6%, while the content of the compound dissolved in ethanol is 3.9%. Total ash content of 2.99%. Non-specific parameters include acid insoluble ash content of 1.03%. The drying rate of geluguric acid simplicia was 7.20%. Water content of sour fruit gelugur extract was 13%.
References
Departemen Kesehatan RI. (2000): Parameter standar umum ekstrak tumbuhan obat, Departemen Kesehatan RI, Jakarta.
Depkes RI, (2008): Farmakope herbal Indonesia edisi I. Departemen Kesehatan Republik Indonesia, Jakarta.
Depkes RI, (2010): Suplemen I farmakope herbal Indonesia edisi I, Departemen Kesehatan Republik Indonesia, Jakarta
Fitriyani, A. (2009): Uji in Vitro Ekstrak Air dan Etanol dari Buah Asam Gelugur, Rimpang Lengkuas, dan Kencur Sebagai Inhibitor Aktivitas Lipase Pankreas, Institut Pertanian Bogor, Bogor.
Gogoi, A., Nabajyoti, G., dan Bijoy, N. (2015): “Dubious anti-obesity agent Hca from Garcinia: A Systematic Review.” International Journal of Pharmacy and Pharmaceutical Sciences 7(7).
Jantan, I., Jumuddin, FA., Saputri, FC., Rahman, K., 2011, Inhibitory effects of
the extracts of Garcinia species on human low-density lipoprotein
peroxidation and platelet aggregation in relation to their total phenolic
contents, J. Med. Plant Res., 5, (2699-2709).
MacKeen, M. M., Mooi, L. Y., Amran, M., Mat, N., Lajis, N. H., dan Ali, A. M. (2012): Noncytotoxic and antitumor-promoting activities of garcinia acid esters from Garcinia atroviridis Griff. ex T. Andres (Guttiferae), Evidance Based Complementary and Alternative Medicine, 1-5.
Saifudin A, Rahayu V, Teruna HY. 2011. Standardisasi bahan obat bahan alam. Yogyakarta. Graha Ilmu.
Widyowati, R., & Rahman, A. (2010): Kandungan Kimia dan Aktivitas Antimikroba Ekstrak Garcinia celebica L. terhadap Staphylococcus aureus, Shigella Dysenteriae dan Candida Albicans, Majalah Farmasi Airlangga, 8 (2), 23-27.
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